Joystiq have an interview up with Dan Connors and Emily Morganti of Telltale Games concerning upcoming adventure Sam & Max.

So, a big element of what we're trying to do is make it something that's very accessible to a wide audience and entertaining. And just keeps people amused in general. So, we're keeping the puzzles focused. There's still some mind-ticklers in there, but it's pretty focused. You're not wandering all over the place in search of puzzles, but it's more of a driven storyline with the puzzles integrated in it. It's really the evolution we see in the genre in general.