Voodoo Extreme have their Best of E3 feature up and I have to say I agree with pretty much every item!

Best of Show - Gears of War (Epic Games)
Was there really any doubt? Gears of War is awesome. It's not just the graphics, or parts of the gameplay, but the overall package. Not that the 360 ever needed a system seller, but if it did, Gears of War is it.

Best Simulation - Spore (EA)
I'll be the first to admit that I'm not the biggest sim fan, but Spore looks interesting nonetheless. Basically, it's Sim World as you can control what life-forms develop, evolve and rule the world. Spore has a really unique visual look too, which adds to its charm.

Best Multiplayer Game - Quake Wars (Splash Damage)
Multiplayer in Doom 3 and Quake IV really blow. Thankfully, id has re-evaluated some of its gameplay philosophies and entrusted the development of Quake Wars to Enemy Territory developer Splash Damage. It's a lot like Battlefield, but is set in the Quake universe. Multiplayer Quake is back!

*** Update ***
After a few more opinions? well they're just a click away. IGN, GameSpot or GameTrailers.