Digital Jesters have issues some brief guidelines for use while playing Trackmania Sunrise for extended periods,

• Take regular breaks whilst playing – at least 10 minutes every hour.
• Sit at least a metre away from the screen.
• Limit upper body movement when playing.
• Switch the view to out-of-car when playing for extended periods.
• Drink plenty of water during playing sessions.

I guess it goes like, errr, really fast.