Set in the post-apocalyptic world of 2281, 200 years after the nuclear war between the US and China that bought the human race to the brink of extinction, the game takes place in the blasted Mojave Wasteland - Nevada, Las Vegas (now renamed New Vegas) and a hundred watering holes, bandit camps, monster lairs, military bases and assorted random encounters spread across the desert sands - not a nice place for a holiday.